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Published on: November 21, 2013
[Search for risk factors for slowed intra-atrial conduction in patients with schizophrenia]
S A Galkin1, E G Kornetova1, V F Lebedeva1
1Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.
Objective:
To study the risk factors for a slowed intra-atrial conduction in patients with schizophrenia.
Material And Methods:
One hundred twenty-two electrocardiograms of patients with schizophrenia who took antipsychotics were analyzed. The components of the metabolic syndrome, as well as anthropometric parameters, were identified as potential risk factors.
Results:
Slowed intra-atrial conduction (P >0.10 s) was found in 21 (17.2%) patients. Therefore, the patients were divided into two groups depending on the presence or absence of slowed intra-atrial conduction. Male sex (p=0.031), the duration of basic therapy (p<0.001), hypertriglyceridemia (p=0.043), the presence of metabolic syndrome (p=0.015), and hypersthenic body type (p<0.001) were statistically significant risk factors for slowed intra-atrial conduction in patients with schizophrenia.
Conclusion:
If these risk factors are identified in patients with schizophrenia, continuous monitoring of the electrocardiogram and pharmacological interventions are recommended for the identified indications.
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