Related Experiment Video
Updated: Jun 13, 2026

IridiumIII Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II
Published on: July 7, 2015
Peptide-based aggregation-induced emission fluorescent probe for rapid and accurate detection of low molecular weight
Yingying Zhu1,2, Meiyu Lin2, Jieman Lin3
1School of Health Sciences and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.
Abstract:
Monitoring low molecular weight heparin (LMWH) is essential in clinical practice. We present a peptide-based aggregation-induced emission fluorescent probe, Z-BTDPA-Pep, capable of rapid, sensitive, and selective detection of LMWH in serum (0.1-2.0 U ml-1, LOD = 0.00378 U ml-1). The results correlate well with the clinical gold-standard anti-Xa assay, highlighting its potential for real-time LMWH monitoring and safer clinical drug administration.
Related Concept Videos
Enzyme-Linked Immunosorbent Assay
There are many different types of ELISAs, but they all involve an antibody molecule whose constant region binds an enzyme, leaving the variable region free to bind its specific antigen. Enzyme-substrate reaction allows the antigen to be visualized or quantified.
High-Performance Liquid Chromatography: Types of Detectors

