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Serum Omics Analysis Reveals Tissue Damage and Metabolic Reprogramming in Cavitary Pulmonary Tuberculosis

Jianhai Wang1,2,3, Dong Zhang4, Chunnan Du1

  • 1Department of Tuberculosis, Haihe Clinical School, Tianjin Medical University, Tianjin 300350, China.

Journal of Proteome Research
|December 9, 2025
PubMed
Summary

Cavitary pulmonary tuberculosis (PTB) involves destructive lung damage. Researchers identified suppressed cell junction proteins and altered metabolism, with DSG4 and amyl salicylate showing potential as biomarkers for this severe TB form.

Keywords:
cavitary pulmonary tuberculosisomics analysisserum

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