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Diabetic Peripheral Neuropathy: New Diagnostics and Treatment Perspectives
Michal Dubský1,2, Dominika Sojáková1,2, Vladimira Fejfarová1,3
1Diabetes Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Drugs & Aging
|December 9, 2025
Summary
Diabetic peripheral neuropathy (DPN) is a major diabetes complication. Annual screening with monofilaments and tuning forks aids early detection and prevention of serious foot issues.
Area of Science:
- Neurology
- Endocrinology
- Diabetology
Background:
- Diabetic peripheral neuropathy (DPN) is a significant, heterogeneous complication of diabetes.
- It affects multiple nervous system parts, causing diverse symptoms and increasing diabetic foot disease risk.
Purpose of the Study:
- To highlight the importance of early diabetic neuropathy diagnosis.
- To emphasize annual screening protocols for identifying DPN and preventing foot complications.
Main Methods:
- Annual screening for DPN using monofilaments and tuning forks (or biothesiometers).
- Focus on early diagnosis and risk identification for diabetic foot disease.
Main Results:
- Early diagnosis is achievable through regular screening.
- Screening identifies individuals at risk for diabetic foot disease, including ulcerations and amputations.
Conclusions:
- Annual DPN screening is crucial for diabetes clinics.
- Prevention of secondary complications like foot ulcerations is paramount.
- Improved screening, prevention, and treatment strategies are needed.
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