Related Experiment Video
Updated: Jun 28, 2026
Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
Trends and factors associated with pneumonia mortality at Buea Regional Hospital in Cameroon from 2020 to 2023
Kukwah Anthony Tufon1,2, Tiayah Patience Foumene1,2, Malika Esembeson2,3
1Department of Microbiology and Parasitology, Faculty of Science, University of Buea, Buea, Cameroon.
Background:
Pneumonia cases and associated deaths remain a public health concern necessitating ongoing efforts in prevention, diagnosis, and treatment. This study was aimed at identifying the trend of pneumonia, case fatality rate and factors associated with pneumonia mortality at the Buea regional hospital from 2020 to 2023.
Methods:
In this retrospective study, data was collected from all available and complete adult inpatient/outpatient hospital records from 2020 to 2023 at Buea regional hospital. Only patients clinically and radiologically diagnosed with pneumonia (excluding TB and COVID-19) were considered for this study. Data was analyzed using SPSS with statistical significance set at p < 0.05.
Results:
After reviewing 18,805 entries/records, 746 files corresponding to 746 patients (59.5% females) diagnosed with pneumonia were retained with mean age of 54.7 ± 19.2 years. There was a fluctuating trend in cases across the years with 2021 generally having higher values. There was a decreasing trend in case fatality rate across the years (2020: 17%, 2021:24%, 2022:8%, 2023:6%) with an overall case fatality rate of 13.7%. Being hospitalized for ≤10 days (aOR: 10.14, CI: 2.31-44.52, p = 0.002) and not being treated with amoxicillin-clavulanic acid (aOR: 3.33, CI: 1.43-7.75, p = 0.005) were significantly associated with pneumonia mortality.
Conclusion:
Although the number of pneumonia cases fluctuated over time, they remained consistently present across all months from 2020 to 2023, highlighting the year-round nature of pneumonia transmission and its endemicity in the Buea Health District. Being hospitalized for less than 10 days and not using amoxicillin-clavulanic acid for treatment were risk factors of pneumonia mortality. These findings underscore the importance of timely diagnosis and empiric treatment with guideline recommended agents such as amoxicillin-clavulanic acid so as to reduce pneumonia mortality in the Buea regional hospital.
More Related Videos
04:32Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
12:21A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
Published on: September 28, 2022
Related Concept Videos
01:30Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
01:29Pneumonia II: Pathophysiology
01:30Pneumonia III: Complications and Assessment
01:28Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
01:30Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
01:29Pneumonia I: Introduction