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The state of science convergence in implantable brain-computer interface clinical trials
K Michelle Patrick-Krueger1,2, Ioannis Pavlidis3, Jose L Contreras-Vidal2
1Texas institute of Restorative Neurotechnology, Department of Neurology, McGovern School of Medicine, University of Texas Health Sciences Houston, Houston, TX 77030, United States of America.
None:
Objective.Advances in implantable brain-computer interfaces (iBCI) have rapidly accelerated in the last decade that promises to improve the quality of life of patients with communications, sensory, and motor control disabilities.Approach.In this Perspective, we quantify the extent and nature of scientific convergence across 21 research groups conducting iBCI clinical trials worldwide. Using medical subject headers and Classification of Instructional Programs taxonomies, we analyze topical and disciplinary integration within 161 publications from 1998-2023 to assess how deeply team composition aligns with research themes and translational impact.Main Results.Our findings indicate uneven patterns of convergence, with many teams combining engineering and clinical expertise yet omitting ethical, legal, and social dimensions. This represents what we term short-cut convergence.Significance.We propose an operational definition of this phenomenon and identify practical steps for researchers and funders to strengthen full convergence to accelerate iBCI translation and implementation.

