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Updated: Jan 9, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
Short conventional IVF, big impact: navigating protocol variations towards standardization
Giorgia Carullo1, Sofia Makieva2, Min Xie1
1Department of Reproductive Endocrinology, University Hospital Zurich, Zurich, Switzerland.
Abstract:
The field of assisted reproductive technology (ART) has undergone substantial progress in recent years, particularly in the refinement of insemination techniques. Despite the widespread use of various methods, however, a definitive consensus on the optimal insemination protocols, particularly within conventional IVF, remains elusive. From oocyte-sperm incubations lasting mere seconds to extended overnight strategies, the variability in approaches has contributed to inconsistent outcomes and practices across fertility clinics. This review critically examines the range of protocols used in short insemination conventional IVF and scrutinizes the underlying rationale behind different incubation durations and methodologies. By summarizing the available evidence, the aim is to discern patterns that could inform the development of a unified protocol, thereby standardizing short conventional IVF practices. Ultimately, this review emphasizes the urgent need for evidence-based guidelines to streamline conventional IVF procedures, ensuring improved clinical outcomes and greater consistency in practice across the global landscape of ART.
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