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Association between transportation noise exposure and type 2 diabetes risk in a French prospective cohort: the
Anita Houeto1, Anne-Sophie Evrard2, Claire Perrin1
1Paris-Saclay University, UVSQ, Inserm, Gustave Roussy, CESP, 16 Avenue Paul-Vaillant Couturier 94807, Villejuif Cedex, France.
Background:
It has been suggested that exposure to transportation noise is associated with an increased risk of type 2 diabetes (T2D), but only a few prospective cohort studies have investigated this hypothesis for railway and aircraft noise. In the BROUHAHA study, we examined this association using data from the E3N-Generations cohort of French women.
Methods:
We included 18,926 women residing in the Île-de-France or Auvergne-Rhône-Alpes regions (France) between 2000 and 2014. Annual average Lden (day-evening-night level) and Ln (night level) values were estimated for road traffic, railway, and aircraft noise using strategic noise maps. Incident T2D cases were identified through follow-up questionnaires and validated using drug reimbursement insurance databases. Cox proportional hazards models were used to calculate adjusted hazard ratios (HRs) and 95 % confidence intervals (CI).
Results:
A 10 dB(A) increase in road traffic noise exposure was associated with a moderate increase in T2D risk (Lden: HR = 1.08, 95 %CI: 1.00, 1.18; Ln: HR = 1.12, 95 %CI: 1.01, 1.25). Adjustment for NO2 and PM2.5 slightly increased the estimated HRs. No association was observed between railway or aircraft noise and T2D incidence.
Conclusion:
In this prospective cohort study of French women, exposure to road traffic noise was associated with a moderate increase in T2D risk, independently of NO2 and PM2.5 exposure. This association was slightly stronger for night-time noise exposure than for day-evening-night exposure.
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