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Related Experiment Video

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Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model
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MGWO-CNN: hyperparameter optimization of CNN classifier for cervical cancer detection using Modified Grey Wolf

Sanat Jain1,2, Ashish Jain3, Mahesh Jangid4

  • 1School of Computing Science Engineering, VIT Bhopal University, Sehore, India.

Scientific Reports
|December 9, 2025
PubMed
Summary

A novel Modified Grey Wolf Optimizer-based Convolutional Neural Network (MGWO-CNN) effectively detects cervical cancer from Pap smear images. This AI approach overcomes common model limitations, achieving high accuracy for early diagnosis and treatment.

Keywords:
Cervical cancerConvolutional neural networkFeature extractionMetaheuristics

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Oncology

Background:

  • Cervical cancer is a significant global health issue with increasing mortality rates.
  • Current detection methods using Convolutional Neural Network (CNN) models often suffer from overfitting and gradient vanishing.
  • Efficient and accurate diagnostic tools are crucial for reducing cervical cancer deaths.

Purpose of the Study:

  • To propose a Modified Grey Wolf Optimizer-based Convolutional Neural Network (MGWO-CNN) for improved cervical cancer detection.
  • To address limitations of traditional CNN models like overfitting and poor convergence.
  • To enhance the accuracy and reliability of cervical cancer diagnosis using AI.

Main Methods:

  • Developed a Modified Grey Wolf Optimizer-based Convolutional Neural Network (MGWO-CNN) integrating chaos theory and differential evolution mutation.
  • Utilized metaheuristic techniques to optimize CNN hyperparameters for effective model training.
  • Extracted key features from cervical Pap smear images for outcome prediction.

Main Results:

  • The MGWO-CNN model demonstrated remarkable effectiveness in detecting cervical cancer.
  • Achieved high performance metrics on the Herlev and SIPaKMeD datasets.
  • Outperformed existing methods with 99.45% accuracy, 100% precision, 97.96% sensitivity, and 100% specificity.

Conclusions:

  • The proposed MGWO-CNN model offers a superior approach for cervical cancer detection.
  • The optimized model provides accurate and reliable predictions from Pap smear images.
  • This AI-driven method has the potential to significantly reduce cervical cancer mortality rates.