Related Experiment Videos
[Nucleolar structure during the prophase of Physarum polycephalum]
Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences. Serie D: Sciences Naturelles
|November 21, 1977
Summary
Electron microscopy revealed unique fibrillar structures within the Physarum polycephalum nucleolus during early prophase. These structures, featuring an electron-lucid center and dense fibrillar component, were studied in relation to ribosomal RNA synthesis.
Area of Science:
- Cell Biology
- Molecular Biology
- Microscopy
Context:
- Investigation of nucleolar structure and function in early prophase.
- Utilizing Sugihara's fixation technique for electron microscopy.
- Focus on the slime mold Physarum polycephalum.
Purpose:
- To identify and characterize specific fibrillar structures within the early-prophase nucleolus.
- To examine the relationship between these structures and ribosomal RNA synthesis rates.
Summary:
- Electron microscopic study of Physarum polycephalum early-prophase nucleoli identified distinct fibrillar structures.
- These structures exhibit a central electron-lucid region surrounded by a dense fibrillar component.
- The study explores the correlation between these 'fibrillar centers' and the rate of ribosomal RNA synthesis.
Impact:
- Provides insights into the ultrastructural organization of the nucleolus during cell division.
- Contributes to understanding the regulation of ribosomal RNA synthesis.
- Highlights the utility of advanced microscopy techniques in cellular research.