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Mobile app improves treatment of functional constipation in children: a randomized single-blind study
Julia Leszkowicz1, Wojciech Nazar2, Karolina Wysokińska-Zakrzewska3
1Department of Paediatrics, Gastroenterology, Allergology & Paediatric Nutrition, Medical University of Gdańsk, Gdańsk, Poland. julia.leszkowicz@gumed.edu.pl.
Insights
A mobile app significantly improved symptom control in children with functional constipation compared to printed materials. This digital health intervention enhances adherence and self-efficacy for better pediatric gastrointestinal health management.
Area of Science:
- Pediatric Gastroenterology
- Digital Health Interventions
- Evidence-Based Medicine
Background:
- Functional constipation is a common pediatric gastrointestinal disorder impacting quality of life and healthcare costs.
- Adherence to treatment guidelines is a significant challenge in managing pediatric functional constipation.
- Mobile health (mHealth) interventions show promise for improving adherence and outcomes.
Purpose of the Study:
- To compare the efficacy of a mobile application versus printed educational materials in managing pediatric functional constipation.
- To assess the impact of a digital intervention on symptom control and quality of life in children with functional constipation.
- To evaluate adherence and self-efficacy in a pediatric functional constipation management program.
Main Methods:
- A randomized, single-blind, per-protocol study involving 100 pediatric patient-caregiver dyads.
- Intervention group used a mobile application; control group received printed educational materials.
- Outcomes measured over six months using the Pediatric Quality of Life Inventory™ (PedsQL™) Gastrointestinal Symptoms Module.
Main Results:
- The mobile application group showed significantly greater improvements in symptom control compared to the printed materials group (21.4 vs. 12.3 points).
- Improvements were particularly noted in domains related to constipation, abdominal pain, and bloating.
- The intervention demonstrated a statistically significant effect on symptom management (p=0.014).
Conclusions:
- Mobile health interventions, featuring interactive tools and rewards, can enhance adherence and self-efficacy in pediatric functional constipation management.
- The study supports the utility of mobile applications as adjuncts to standard care for pediatric functional constipation.
- Digital health tools offer a valuable approach to improving therapeutic success in managing chronic pediatric conditions.
Background:
Functional constipation is one of the most prevalent functional gastrointestinal disorders in the pediatric population, frequently resulting in quality of life impairment and elevated healthcare costs. Despite the availability of evidence-based treatment guidelines, adherence remains an essential challenge to achieving sustained therapeutic success.
Methods:
This randomized, single-blind per-protocol study assessed the efficacy of a mobile application compared to conventional printed educational materials in supporting the management of functional constipation in children aged 4-12 years. 100 patient-caregiver dyads were randomized into two arms: an intervention group using a mobile application and a control group receiving printed recommendations. Clinical outcomes were evaluated over a six-month follow-up using the Pediatric Quality of Life Inventory™ (PedsQL™) Gastrointestinal Symptoms Module.
Results:
There were 113 complete questionnaires, 65 from adults and 48 from children. Participants in the intervention cohort demonstrated significantly greater improvements in symptom control (mean difference 21.4 vs. 12.3 points; p = 0.014), particularly in the domains of constipation, abdominal pain, and bloating.
Conclusions:
The mobile application's interactive features, behavioral tracking tools, and integrated reward system appeared to enhance adherence and self-efficacy among users. Overall, the results support the potential utility of mobile health interventions as adjuncts to standard care in managing pediatric functional constipation.
Trial Registration:
ClinicalTrials.gov NCT07025135. Registered 17/06/2025 (trial start 05/02/2023).
Trial Registration:
ClinicalTrials.gov NCT07025135. Registered 17/06/2025 (trial start 05/02/2023).
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