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Swin-PSAxialNet: An Efficient Multi-Organ Segmentation Technique
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Retinal vessel segmentation using multi scale feature attention with MobileNetV2 encoder.

Tanishq Soni1, Sheifali Gupta2, Salil Bharany2

  • 1Chitkara University Institute of Engineering and Technology, Chitkara University, Punjab, Punjab, India. tanishq.soni@chitkara.edu.in.

Scientific Reports
|December 9, 2025
PubMed
Summary
This summary is machine-generated.

This study presents MSFAUMobileNet for retinal blood vessel segmentation, crucial for early disease detection. The model achieves high accuracy, aiding in diagnosing conditions like diabetic retinopathy and glaucoma.

Keywords:
Attention mechanismDiabetic retinopathyGlaucomaMobileNetV2Multi-Scale feature aggregation (MSFA)Residual connectionsRetinal vessel segmentationU-Net architecture

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Area of Science:

  • Medical Imaging
  • Computer Vision
  • Ophthalmology

Background:

  • Retinal blood vessel segmentation is vital for diagnosing diseases like diabetic retinopathy, glaucoma, and AMD.
  • Accurate segmentation aids in early detection and monitoring of retinal conditions.
  • Existing methods may struggle with the complexity of retinal vascular networks.

Purpose of the Study:

  • To introduce the MSFAUMobileNet model for enhanced retinal blood vessel segmentation.
  • To improve the accuracy and efficiency of retinal image analysis for disease detection.
  • To provide a computationally efficient tool for clinical practice.

Main Methods:

  • Developed MSFAUMobileNet, a U-Net architecture incorporating Multi-Scale Feature Aggregation (MSFA), residual connections, and attention mechanisms.
  • Employed MobileNetV2 as the encoder to extract hierarchical features from 13 bottleneck layers.
  • Integrated MSFA to capture spatial information across multiple resolutions for precise vascular network outlining.

Main Results:

  • The MSFAUMobileNet model achieved exceptional performance on the DRIVE dataset.
  • Achieved high segmentation accuracy (99.99%), Dice coefficient (99.95%), and Intersection over Union (IoU) (99.94%).
  • Demonstrated efficient separation of complex retinal vascular networks.

Conclusions:

  • MSFAUMobileNet significantly improves retinal blood vessel segmentation accuracy and efficiency.
  • The model's precision and speed make it suitable for medical image analysis in clinical settings.
  • Facilitates early diagnosis and management of retinal diseases through advanced image analysis.