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Related Concept Videos

Olfaction01:25

Olfaction

48.0K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
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Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

11.1K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
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Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

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Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
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High Resolution Physical Characterization of Single Metallic Nanoparticles
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Active Polymer-Templated Porous Metal Oxide Nanospheres with Tailored Single-Atom Modification for Olfactory

Keyu Chen1, Liyuan Zhu2, Jianwu Wang3,4

  • 1Department of Chemistry, Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Coatings for Advanced Equipment, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, Shanghai 200433, P. R.China.

Journal of the American Chemical Society
|December 10, 2025
PubMed
Summary

Researchers developed a new method to create uniform porous metal oxide semiconductor nanospheres. These functionalized nanospheres enable high-performance gas sensors with tailored selectivity and sensitivity for advanced applications.

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Chemical Engineering

Background:

  • Controllable synthesis of monodisperse porous metal oxide semiconductor (MOS) nanospheres is crucial for high-performance nanodevices.
  • Existing methods face challenges due to precursor hydrolysis and insufficient coassembly.
  • Uniform size and tailored chemical environments are key requirements.

Purpose of the Study:

  • To propose a novel polymer-directing method for synthesizing uniform functionalized mesoporous MOS nanospheres.
  • To demonstrate the synthesis of single-atom modified mesoporous tin dioxide (SnO2) nanospheres (SA/mSnO2).
  • To develop stable gas-sensing inks and wafer-scale fabrication of sensors.

Main Methods:

  • Utilized single-atom-modified mesoporous polydopamine nanospheres as intermediates.
  • Employed phenolic hydroxyl and imine groups for SnO2 skeleton formation and single-atom stabilization.
  • Prepared gas-sensing inks for high-speed printing on microelectromechanical systems (MEMS) chips.

Main Results:

  • Successfully synthesized uniform SA/mSnO2 nanospheres with tailored single-atom modifications.
  • Developed stable gas-sensing inks enabling wafer-scale fabrication.
  • Achieved sensors with tailored selectivity, 5.6x higher sensitivity than commercial sensors, and excellent consistency.
  • Integrated SA/mSnO2 devices into an intelligent olfactory system for an automated guided vehicle.

Conclusions:

  • The proposed colloidal polymer-directing method facilitates the facile synthesis of uniform functionalized mesoporous MOS nanospheres.
  • SA/mSnO2 nanospheres enable high-performance gas sensors with improved selectivity and sensitivity.
  • The developed technology supports wafer-scale fabrication and integration into intelligent systems for chemical detection.