Sepsis after the Altemeier procedure: A case report

Jiameng Zhu1, Lin Liu1, Hezhai Yin1,2

  • 1Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China.

Medicine
|December 10, 2025
PubMed
Abstract

Insights

Sepsis from anastomotic leakage after the Altemeier procedure is rare. Early intervention with ileostomy and targeted therapy successfully treated a patient with rectal prolapse and sepsis.

Area of Science:

  • Gastroenterology
  • Surgical Complications
  • Infectious Disease

Background:

  • Anastomotic leakage is a critical complication of the Altemeier procedure.
  • Sepsis secondary to anastomotic leakage is infrequently reported.

Purpose of the Study:

  • To report a rare case of sepsis resulting from anastomotic leakage after the Altemeier procedure.
  • To highlight the management of severe sepsis and anastomotic leakage in a patient with rectal prolapse and comorbidities.

Main Methods:

  • A patient with rectal prolapse underwent the Altemeier procedure and subsequently developed sepsis and anastomotic leakage.
  • Management involved terminal ileostomy, irrigation-drainage catheter placement, and broad-spectrum antibiotics (meropenem and levofloxacin).

Main Results:

  • The patient's sepsis and infection markers (procalcitonin, C-reactive protein) resolved within 22 days.
  • Complete anastomotic healing was confirmed by colonoscopy at 4 months, allowing for successful ileostomy reversal.

Conclusions:

  • Thorough preoperative assessment is vital for patients with rectal prolapse and comorbidities to prevent severe anastomotic leakage.
  • Aggressive source control and antimicrobial therapy are crucial for managing sepsis post-Altemeier procedure.