Acute Massive Hydroxychloroquine Overdose of 60 g in an Adult, Successfully Resuscitated: A Successful Salvage

We present the case of a 29-year-old female who ingested a 60 g dose of hydroxychloroquine in a suicide attempt. This report details the acute clinical presentation, successful management strategies, and prolonged sequelae of severe hydroxychloroquine toxicity, including recurrent and delayed episodes of Torsades de Pointes (TdP) and profound metabolic derangements. Early recognition, intensive supportive care, and the use of targeted interventions-including activated charcoal administration, meticulous electrolyte correction, and vasoactive support-were critical to successful management. This case underscores the importance of prompt intervention in hydroxychloroquine overdoses and provides a review of the pathophysiology and therapeutic strategies informed by current literature and our clinical experience.