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Appendiceal Perforation From Muscular Thinning in Limited Cutaneous Systemic Sclerosis: A Case Report
Yuki Nakamura1, Goshi Fujimoto1, Satoshi Matsuda2
1Gastroenterological Surgery, Kameda Medical Center, Kamogawa, JPN.
Cureus
|December 10, 2025
Summary
Systemic sclerosis (SSc) can cause severe intestinal fragility, leading to rare bowel perforations. Surgeons managing SSc patients should consider stoma creation to prevent anastomotic failure and improve outcomes.
Area of Science:
- Gastroenterology
- Rheumatology
- Vascular Medicine
Background:
- Systemic sclerosis (SSc) is a fibrotic autoimmune disease affecting multiple organs.
- Gastrointestinal complications are frequent in SSc, but bowel perforation is uncommon and severe.
- Vasculopathy and fibrosis are key pathological features of SSc.
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