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Related Experiment Video

Updated: Jun 27, 2026

Doppler Optical Coherence Tomography of Retinal Circulation
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Quantitative measurement using panretinal optical coherence tomography with three-dimensional curve distortion

Yakub A Bayhaqi1, Shuibin Ni1, Ringo Ng1

  • 1Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.

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|December 10, 2025
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A new curve correction method improves the accuracy of widefield retinal imaging using Panretinal optical coherence tomography (PanOCT). This technique enhances geometric fidelity, enabling precise measurements for clinical and research applications.

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Panretinal optical coherence tomography (PanOCT) offers widefield retinal imaging up to 140°.
  • Raw PanOCT B-scan images suffer from curvature distortion, hindering quantitative accuracy.

Purpose of the Study:

  • To develop and validate a curve correction method for PanOCT B-scan images.
  • To restore geometric fidelity and improve quantitative accuracy in widefield retinal imaging.

Main Methods:

  • A novel curve correction algorithm was developed for PanOCT images.
  • Validation was performed using a 3D-printed eye phantom.
  • Clinical comparisons were made against Computed Tomography (CT) and ultrasound imaging.

Main Results:

  • The curve correction method achieved average relative errors under 1% in phantom validation.
  • Clinical comparisons showed minimal errors of 2.78% with CT and 5.97% with ultrasound.
  • The corrected images demonstrated strong agreement with standard imaging modalities.

Conclusions:

  • The developed curve correction method effectively restores geometric fidelity to PanOCT images.
  • This technique supports the accurate measurement of widefield retinal structures.
  • PanOCT, with this correction, is a valuable tool for clinical and research ophthalmology.