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Updated: May 5, 2026

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
Published on: January 15, 2013
Ultrahigh-resolution spectral domain optical coherence tomography with a blue-diode-pumped Ti:sapphire laser and an
Manuel Zeyen1, Karlo Lajtner1, Gregory Zaugg2
1Photonic Ultrafast Systems Group, School of Engineering and Environment, University of Applied Sciences and Arts Northwestern Switzerland (FHNW), Klosterzelgstrasse 2, Windisch, CH-5210, Switzerland.
Abstract:
We present a novel, low-cost ultrahigh-resolution optical coherence tomography (OCT) system, based on a broadband blue-diode-pumped Kerr-lens mode-locked Ti:sapphire laser and an axicon lens to achieve high axial and lateral resolutions, respectively. With our spectral domain OCT system, we demonstrate a lateral resolution of < 3 µm and an axial resolution of 4.5 µm in air, corresponding to 3 µm resolution in biomedical tissue. Using this system, we present biomedical images of challenging biomedical tissues, namely highly transparent collagen hydrogel and opaque bone marrow.
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