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The Fading Art of Microsphere-Derived Measurement of Absolute Myocardial Blood Flow

Timothy F Christian1,2

  • 1Professor of Medicine, Albert Einstein College of Medicine, New York, USA.

Annals of Nuclear Cardiology
|December 10, 2025
PubMed

Keywords:
Cardiac imagingCoronary blood flowMicrospheres

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Blood Flow

Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.