Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Function Tests01:25

Pulmonary Function Tests

Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Beyond general depression: Premenstrual interpersonal anger as a unique pathway to suicidal ideation in adolescent females with ADHD.

Journal of psychosomatic research·2026
Same author

Horizontal transfer of a 180-kbp genomic fraction among the largest viral genomes.

Applied and environmental microbiology·2026
Same author

Developmental shift in the functional role of mind-wandering: A large-scale study on adaptive resources against depression in psychiatric outpatients.

Psychiatry research·2026
Same author

Health-Related Quality of Life and Its Related Factors in Adolescents and Adults With Prader-Willi Syndrome in Japan.

American journal of medical genetics. Part A·2026
Same author

Clinical characteristics associated with non-suicidal self-injury among Japanese adolescents-Relationship between non-suicidal self-injury and psychosomatic symptoms: a retrospective cross-sectional study.

BMC psychiatry·2026
Same author

Spinal hypomyelination in a child with classic hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC): expanding the neuroradiological spectrum, a case report.

Brain & development·2026
Same journal

Biallelic Variants in MIMS1 Produce a Form of Spondyloepimetaphyseal Dysplasia With Tracheal Stenosis and Ectodermal Dysplasia (SEMDTSED).

American journal of medical genetics. Part A·2026
Same journal

How does Léri-Weill Dyschondrosteosis Affect Adults' Health-Related Quality of Life? - A Norwegian Cross-Sectional Study Exploring the Physical and Mental Burden.

American journal of medical genetics. Part A·2026
Same journal

Re-Identification of the Panamanian Guna/Kuna/Cuna OCA2 Founder Association Through Two American-Born Siblings.

American journal of medical genetics. Part A·2026
Same journal

Biallelic Variant in HAPLN1 is Associated With Skeletal Dysplasia With or Without Congenital Heart Disease.

American journal of medical genetics. Part A·2026
Same journal

MYH11-Related Hereditary Type 2 Visceral Myopathy in a Large Kindred: Diagnostic Odyssey With Milder Clinical Manifestations.

American journal of medical genetics. Part A·2026
Same journal

Positron Emission Tomography (PET) in Phenylketonuria: A Systematic Review of Brain Metabolism Beyond Phenylalanine.

American journal of medical genetics. Part A·2026
See all related articles

Related Experiment Video

Updated: Jun 19, 2026

A Novel Method for Assessing Proximal and Distal Forelimb Function in the Rat: the Irvine, Beatties and Bresnahan IBB Forelimb Scale
12:46

A Novel Method for Assessing Proximal and Distal Forelimb Function in the Rat: the Irvine, Beatties and Bresnahan IBB Forelimb Scale

Published on: December 16, 2010

20.4K

Functional Independence in Adults With Prader-Willi Syndrome: First Report Using the FIM Instrument.

Yuji Oto1, Hiroyuki Ogata2, Erina Nakane2

  • 1Department of Pediatrics, Dokkyo Medical University Saitama Medical Center, Saitama, Japan.

American Journal of Medical Genetics. Part A
|December 10, 2025
PubMed
Summary
This summary is machine-generated.

In adults with Prader-Willi Syndrome (PWS), age did not significantly correlate with functional independence. Continued support into adulthood is crucial for maintaining quality of life in PWS patients.

Keywords:
Prader–Willi syndromeadaptive functioningadulthoodcognitive declinefunctional Independence measure (FIM)genetic subtype

More Related Videos

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study
06:58

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study

Published on: November 6, 2015

10.2K
Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools
11:29

Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools

Published on: June 20, 2020

9.6K

Related Experiment Videos

Last Updated: Jun 19, 2026

A Novel Method for Assessing Proximal and Distal Forelimb Function in the Rat: the Irvine, Beatties and Bresnahan IBB Forelimb Scale
12:46

A Novel Method for Assessing Proximal and Distal Forelimb Function in the Rat: the Irvine, Beatties and Bresnahan IBB Forelimb Scale

Published on: December 16, 2010

20.4K
A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study
06:58

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study

Published on: November 6, 2015

10.2K
Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools
11:29

Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools

Published on: June 20, 2020

9.6K

Area of Science:

  • Neurology
  • Genetics
  • Developmental Pediatrics

Background:

  • Previous studies show age correlates with functional independence in pediatric Prader-Willi Syndrome (PWS) using the WeeFIM.
  • No studies have assessed functional independence in adults with PWS using the Functional Independence Measure (FIM).

Purpose of the Study:

  • To evaluate functional independence in adults with PWS using the FIM.
  • To explore the impact of age and genetic subtype on functional outcomes in adult PWS patients.

Main Methods:

  • Retrospective, single-center study.
  • Involved 54 genetically confirmed adult patients with PWS of Japanese descent.
  • Utilized the Functional Independence Measure (FIM) for assessment.

Main Results:

  • No significant correlation was found between age and FIM scores in adult PWS patients.
  • No significant differences in total, motor, or cognitive FIM scores were observed across age groups or genetic subtypes.
  • Radar chart analysis suggested a trend towards lower FIM scores in older adults, but this was not statistically significant.

Conclusions:

  • Age and genetic subtype do not appear to be significant predictors of functional independence in adults with PWS.
  • Individualized support plans are essential for adults with PWS.
  • Early intervention and sustained support throughout adulthood are vital for enhancing independence and quality of life in PWS individuals.