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mRNA-based therapies: current progress and future prospects for treating kidney disease
Yiyun Song1, Hua Su2
1Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Abstract:
Approximately, 1.2 million deaths occur each year from chronic kidney disease worldwide. The incidence is increasing and current treatments have limited efficacy. Many patients with kidney disease inevitably end up with kidney replacement therapy. mRNA has revolutionized the world of molecular therapy and spotlighted the attention of the medical community on its potential clinical application. Currently, mRNA-based therapies have started to emerge in the kidney field. In this review, we describe recent advances in renal mRNA-based therapies and discuss future possibilities for using mRNAs to treat kidney diseases.
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