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Related Concept Videos

Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

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Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
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Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
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Post-traumatic headache phenotypes and clinical characteristics.

Achelle Cortel-LeBlanc1,2, Miguel Cortel-LeBlanc2,3, Richard J Webster4,5

  • 1Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.

Cephalalgia : an International Journal of Headache
|December 10, 2025
PubMed
Summary
This summary is machine-generated.

Post-traumatic headache (PTH) following mild traumatic brain injury often presents with daily, severe head pain. This condition significantly impacts daily life, with high rates of psychiatric comorbidities and functional impairment.

Keywords:
cohortconcussionheadache attributed to traumamigrainephenotypepost-traumatic headache

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Area of Science:

  • Neurology
  • Neuroscience
  • Public Health

Background:

  • Post-traumatic headache (PTH) shares features with migraine and tension-type headaches but requires distinct characterization.
  • Mild traumatic brain injury (mTBI) can lead to persistent headache, impacting quality of life.

Purpose of the Study:

  • To characterize the clinical phenotype, headache patterns, associated symptoms, comorbidities, medication use, and functional impact of PTH in adults post-mTBI.
  • To identify distinct features of PTH compared to primary headache disorders.

Main Methods:

  • Cross-sectional analysis of 405 adult patients with PTH after mTBI.
  • Data collected via standardized questionnaires at a specialized concussion and headache center.
  • Descriptive statistics used to analyze clinical features, functional impact, and comorbidities.

Main Results:

  • Most patients (72.1%) experienced headache ≥26 days/month, often continuous (28.1%) or lasting hours to days (53.1%).
  • Headache was typically pulsating/throbbing (64.2%), severe (median 7/10), and associated with photophobia (88.4%), phonophobia (83.2%), and nausea/vomiting (69.0%).
  • High rates of psychiatric comorbidities (49.6%), medication overuse (53.8% using acute meds ≥3 days/week), and functional impairment (41.7% off work/school) were observed.

Conclusions:

  • PTH exhibits distinct features, including frequent, long-duration headaches, suggesting potential early central sensitization.
  • High prevalence of psychiatric comorbidities, medication overuse, and functional impairment necessitates comprehensive management strategies.
  • Further research is needed to differentiate PTH from primary migraine longitudinally and understand pathophysiological mechanisms.