Contrastive independent component analysis for salient patterns and dimensionality reduction
Kexin Wang1, Aida Maraj2, Anna Seigal1
1School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138.
Abstract:
In recent years, there has been growing interest in jointly analyzing a foreground dataset, representing an experimental group, and a background dataset, representing a control group. The goal of such contrastive investigations is to identify salient features in the experimental group relative to the control. Independent component analysis (ICA) is a powerful tool for learning independent patterns in a dataset. We generalize it to contrastive ICA (cICA). For this purpose, we devise a linear algebra-based tensor decomposition algorithm, which is more expressive but just as efficient and identifiable as other linear algebra-based algorithms. We establish the identifiability of cICA and demonstrate its performance in finding patterns and visualizing data, using synthetic, semisynthetic, and real-world datasets, comparing the approach to existing methods.
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