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Updated: Jan 9, 2026

Author Spotlight: Investigating HR-Dependent Cardiac Function in Mouse Models Through a Novel Atrial-Pacing Approach
Published on: July 21, 2023
Diastolic dysfunction in primary care: medical and nursing interlocutions
Adson Renato Leite1, Aretha Pereira de Oliveira2, Dalmo Valério Machado de Lima1
1Universidade Federal Fluminense. Niterói, RJ, Brazil.
Objectives:
To evaluate the ratio between early and late mitral filling velocities (E/A) as a prognostic factor for hospitalizations due to cardiovascular causes and mortality in primary care; to identify the main NANDA-I nursing diagnoses, interventions, and outcomes associated with diastolic dysfunction.
Method:
633 individuals were recruited for evaluation of the E/A ratio and characterization of diastolic dysfunction. Multivariate Cox regression with Schoenfeld residual analysis, survival analysis, and hazard ratio estimation were performed.
Results:
After six years, crude hazard ratios of 3.47, 3.60, 3.02, and 0.41 were identified for classes II and III diastolic dysfunction at cut-off points 1 and 2, respectively (p<0.01). Nursing diagnoses of Activity Intolerance, Anxiety, Fatigue, and Deficient Knowledge should be prioritized.
Conclusion:
The E/A ratio showed an altered pattern in most participants without a diagnosis of heart failure, which may indicate a subclinical form of the condition.
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