Related Experiment Video
Updated: Jan 9, 2026
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Side effects of hormone therapy in patients with malignant breast neoplasm: a cross-sectional study
Erilaine de Freitas Corpes1, Romel Jonathan Velasco Yanez1, Cristina Poliana Rolim Saraiva Dos Santos1
1Universidade Federal do Ceará. Fortaleza, Ceará, Brazil.
Objectives:
to evaluate the side effects of hormone therapy in patients with malignant breast neoplasia.
Methods:
a cross-sectional, analytical study conducted in a mastology outpatient clinic in Ceará, Brazil. Seventy-five women with breast cancer using tamoxifen or aromatase inhibitors were included and classified into four subgroups based on the type and duration of therapy. Fisher's exact test was used to assess the association between associated factors and the occurrence of side effects.
Results:
women using tamoxifen for >12 months had more sexual complaints. Hot flashes, musculoskeletal pain, and fatigue predominated in the anastrozole groups. There was a statistically significant association between side effects and daily lifestyle habits, previous treatment, and calcium replacement therapy.
Conclusions:
all groups presented some side effects and there are some factors that can intensify these symptoms, therefore, health professionals should monitor these effects to intervene early.
Related Concept Videos
02:57Targeted Cancer Therapies
There are several types of targeted therapies against...
02:49Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...