Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Endoscopic Studies I: Bronchoscopy and Thoracoscopy

Endoscopic Studies I: Bronchoscopy and Thoracoscopy

Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Systemwide Implementation of a Multidisciplinary Clinical Pathway for Malignant Pleural Effusion Reduces Interventions, Hospitalizations, and Costs.

Journal of bronchology & interventional pulmonology·2025

Same author

Safety and feasibility of ultrathin probe transbronchial lung cryobiopsy without balloon blocker <i>via</i> robotic bronchoscopy in the evaluation of peripheral lung lesions: a retrospective pilot study.

ERJ open research·2023

Same author

Current Practices Supporting Rigid Bronchoscopy-An International Survey.

Journal of bronchology & interventional pulmonology·2022

Same author

Safety and Efficacy of Manual Aspiration Via Small Bore Chest Tube in Facilitating the Outpatient Management of Transbronchial Biopsy-related Iatrogenic Pneumothorax.

Journal of bronchology & interventional pulmonology·2021

Same author

Pleural Catheter Fracture During IPC Removal: An Under-reported Complication.

Journal of bronchology & interventional pulmonology·2020

Same author

Ambulatory Iodopovidone Instillation Via Indwelling Pleural Catheters For Malignant Pleural Effusions.

Journal of bronchology & interventional pulmonology·2019

Search research articles

Related Experiment Video

Updated: Jan 9, 2026

Author Spotlight: Expanding Interventional Pulmonology Research with Robotic-Assisted Bronchoscopy

Author Spotlight: Expanding Interventional Pulmonology Research with Robotic-Assisted Bronchoscopy

Published on: July 19, 2024

Proceduralist-Directed Rapid On-Site Pathologic Evaluation (ROPE) Using Dynamic Cell Imaging: A Pilot Study of

Ismael Matus¹, Sameer Akhtar², Haroon Raja¹

¹Thoracic Surgery and Interventional Pulmonology Service, Helen F. Graham Cancer Center and Research Institute.

Journal of Bronchology & Interventional Pulmonology

|December 10, 2025

Summary

Rapid onsite pathologic evaluation (ROPE) using Dynamic Cell Imaging (DCI) for peripheral pulmonary lesions (PPLs) shows high concordance with final pathology. This technology improves diagnostic confidence during procedures.

Keywords:

bronchoscopy cryobiopsy dynamic cell imaging (DCI)fine needle aspiration forceps biopsy lymph node peripheral pulmonary lesions (PPLs)rapid onsite evaluation (ROSE)rapid onsite pathologic evaluation (ROPE)

More Related Videos

Author Spotlight: Advancing Pathogen Detection and Disease Assessment in Real-Time Using M-ROSE

Author Spotlight: Advancing Pathogen Detection and Disease Assessment in Real-Time Using M-ROSE

Published on: March 1, 2024

Subcostal Specimen Removal in Completely Portal Robotic Lobectomy

Subcostal Specimen Removal in Completely Portal Robotic Lobectomy

Published on: April 19, 2024

Related Experiment Videos

Last Updated: Jan 9, 2026

Author Spotlight: Expanding Interventional Pulmonology Research with Robotic-Assisted Bronchoscopy

Author Spotlight: Expanding Interventional Pulmonology Research with Robotic-Assisted Bronchoscopy

Published on: July 19, 2024

Author Spotlight: Advancing Pathogen Detection and Disease Assessment in Real-Time Using M-ROSE

Author Spotlight: Advancing Pathogen Detection and Disease Assessment in Real-Time Using M-ROSE

Published on: March 1, 2024

Subcostal Specimen Removal in Completely Portal Robotic Lobectomy

Subcostal Specimen Removal in Completely Portal Robotic Lobectomy

Published on: April 19, 2024

Area of Science:

Pulmonology
Pathology
Medical Technology

Background:

Peripheral pulmonary lesions (PPLs) evaluation often requires multiple diagnostic tools.
Rapid onsite evaluation (ROSE) is established for mediastinal lymph nodes but less studied for PPLs.
Dynamic Cell Imaging (DCI) offers potential for intraprocedural histopathologic analysis of PPLs.

Purpose of the Study:

To quantify the concordance between rapid onsite pathologic evaluation (ROPE) using DCI and a pathologist's final diagnosis for PPLs.
To assess the utility of DCI in improving diagnostic confidence during PPL evaluation.

Main Methods:

A single-center study involving robotic bronchoscopic evaluation of PPLs.
Samples were obtained using fine needle aspiration, cryobiopsy, and forceps biopsy.
Proceduralists used DCI for initial interpretation, followed by a pathologist's final diagnosis; concordance was calculated at patient and biopsy levels.

Main Results:

Fifty patients and 146 samples were analyzed.
Overall patient-level concordance between DCI interpretation and final pathology was 88%.
Biopsy-level concordance was 84%, with highest agreement for cryobiopsy (88%) and forceps biopsy (86%).

Conclusions:

ROPE utilizing cryoprobe and forceps biopsy for PPLs demonstrates high concordance with final pathology.
This approach enhances intraprocedural confidence in obtaining diagnostic specimens.
Further research is needed to explore DCI's impact on diagnostic yields and its role in future bronchoscopic treatments.