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Minimal Detectable Change for Grip Strength and Gait Speed in Older Japanese Adults With Sarcopenia

Lu Yin1, Yohei Sawaya2,3, Ryo Sato1

  • 1Integrated Facility for Medical and Long-Term Care, Care Facility for the Elderly "Maronie-En,", Nasushiobara, Tochigi, Japan.

Geriatrics & Gerontology International
|December 10, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Japangaithand strengthlong‐term caresarcopenia

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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