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Updated: Jan 9, 2026
![[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59739.jpg&w=3840&q=50)
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Red-Light-Driven Recyclable mpg-C3N4-Catalyzed Minisci Reaction: Access to Heterocycle-Substituted
Chenya Wang1, Jianyang Dong1, Yajun Sun1
1Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education and School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710119, People's Republic of China.
None:
The first red-light-driven Minisci reaction of heteroarenes with a readily available BCP-derived redox-active ester (RAE) has been developed, employing mesoporous graphitic carbon nitride (mpg-C3N4) as a recyclable heterogeneous photocatalyst. The heterogeneous nature of mpg-C3N4 allows for easy recovery and reuse, maintaining a high catalytic activity over five consecutive cycles. This approach provides efficient access to heterocycle-functionalized BCP scaffolds, which are of high interest in medicinal chemistry as potential bioisosteres of biaryl scaffolds. Notably, the photoredox reactions proceed smoothly under sunlight irradiation, and a successful scale-up demonstration highlights its promise for industrial applications.
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