Related Experiment Video
Updated: Jan 9, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
Increasing the pneumonia treatment coverage among children under 5 years old through 'Enhanced Management of
Humphreys Nsona1, Emmanuel Golombe2, Ulemu Zulu2
1IMCI Unit, Government of Malawi Ministry of Health, Lilongwe, Central Region, Malawi.
Insights
This study expands pneumonia management in Malawi by training Health Surveillance Assistants to treat chest indrawing and fast-breathing pneumonia in young children within the community. Findings will inform national child health strategies.
Area of Science:
- Public Health
- Global Health
- Implementation Science
Background:
- Pneumonia is a leading cause of under-5 mortality in sub-Saharan Africa, with Malawi reporting over 110,000 cases in six months.
- Malawi's Integrated Community Case Management (iCCM) strategy reduced child mortality but excludes specific pneumonia types in infants and young children.
- This research addresses gaps in current pneumonia management protocols for children under five.
Purpose of the Study:
- To assess the feasibility and acceptability of expanding the iCCM strategy to include chest indrawing and fast-breathing pneumonia management at the community level.
- To increase pneumonia treatment coverage for children under five in Kasungu District, Malawi.
- To evaluate the role of Health Surveillance Assistants (HSAs) in community-based pneumonia case management.
Main Methods:
- Implementation research utilizing qualitative and quantitative data collection.
- Trained HSAs will manage fast-breathing pneumonia in infants (7-59 days) and chest indrawing pneumonia in children (2-59 months) with oral amoxicillin.
- Pulse oximetry will be used to identify hypoxemic children for referral; treatment compliance and coverage will be assessed via surveys.
Main Results:
- This section is to be filled once the study is completed and results are available.
Conclusions:
- This section is to be filled once the study is completed and conclusions are drawn.
Introduction:
Pneumonia remains a leading cause of under-5 mortality in sub-Saharan Africa, accounting for approximately 14% of deaths in this age group. In Malawi, pneumonia accounts for 12% of under-5 deaths, with recent data revealing a concerning trend of over 110 000 new cases reported in 6 months. The Malawi government has made significant strides in reducing childhood mortality through the Integrated Community Case Management (iCCM) strategy, resulting in an 11% reduction in under-5 mortality over a 5-year period. However, the current iCCM strategy does not include the management of chest indrawing pneumonia in children aged 2-59 months and fast-breathing pneumonia in infants aged up to 2 months. This implementation research aims to increase pneumonia treatment coverage for under-5 year-old children in Kasungu District, Malawi, by expanding the community-based management of pneumonia by the iCCM-trained Health Surveillance Assistants (HSAs).
Methods And Analysis:
The current implementation research using both qualitative and quantitative data collection methods will assess the feasibility and acceptability of iCCM-trained HSAs managing chest indrawing pneumonia and fast-breathing pneumonia in children under 5 with oral amoxicillin at the community level in district Kasungu using the existing district health system. The study will employ a district health system model, leveraging existing trained iCCM HSAs to enrol and manage infants aged 7-59 days with fast-breathing pneumonia and 2-59-month-old children with chest indrawing pneumonia in the community with 7-day and 5-day oral amoxicillin, respectively. HSAs will also use pulse oximetry to identify hypoxaemic children for prompt referral to a hospital for further care. Sociodemographic features of enrolled children will be documented. Enrolled children will be followed up on treatment compliance using follow-up forms. The pneumonia treatment coverage will be assessed using baseline, midline and end-line surveys using both qualitative and quantitative data collection methods.
Ethical And Dissemination:
Ethical approval was obtained from the National Health Research Sciences Committee and the WHO Ethics Committee. The implementation research findings will be disseminated to national-level stakeholders and specifically targeted at District Health Offices, which are responsible for implementing the interventions.
Related Concept Videos
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Pneumonia III: Complications and Assessment
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Chronic Obstructive Pulmonary Disease-V: Nursing Management
Assessment
Pneumonia II: Pathophysiology

