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The first successfully cloned mammal was Dolly, a sheep, born on 5th July 1996 at Roslin Institute, Scotland. The cloned sheep was named after the American singer Dolly Parton. Dolly lived for seven years and died of respiratory complications, which is speculated to be due to the actual age of her DNA. Because the DNA in cloned cells belongs to an older individual,  the cloned individual’s life expectancy may be affected. Indeed, analysis of Dolly’s DNA revealed shorter...
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Reproductive cloning is the process of producing a genetically identical copy—a clone—of an entire organism. While clones can be produced by splitting an early embryo—similar to what happens naturally with identical twins—cloning of adult animals is usually done by a process called somatic cell nuclear transfer (SCNT).
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Updated: Jan 9, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
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Assisted Reproduction Therapy in Patients with Multiple Sclerosis: Narrative Review and Practical Recommendations.

Lenka Mekiňová1,2, Iva Šrotová2,3, Petra Hanáková2,4,5

  • 1Department of Gynecology and Obstetrics, University Hospital Brno, 625 00 Brno, Czech Republic.

Healthcare (Basel, Switzerland)
|December 11, 2025
PubMed
Summary

Assisted reproductive technology (ART) does not increase the risk of developing multiple sclerosis (MS). Current evidence indicates ART is safe for women with MS undergoing fertility treatments, with individualized care crucial for pregnancy success.

Keywords:
IVFagonist protocolantagonist protocolautoimmune diseasemultiple sclerosisovarian stimulation

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Area of Science:

  • Reproductive Medicine
  • Neurology
  • Immunology

Background:

  • Assisted reproductive technology (ART) use is rising globally for infertility.
  • Autoimmune disease incidence is increasing, with ART being investigated as a potential factor.
  • Existing research on ART and autoimmune disorders, specifically multiple sclerosis (MS), yields inconsistent conclusions.

Purpose of the Study:

  • To review current evidence on the association between assisted reproduction and multiple sclerosis incidence.
  • To evaluate the safety and efficacy of ART in women with MS.

Main Methods:

  • This study employed a narrative review design.
  • Analysis of recent extensive studies investigating the link between infertility treatments and MS development.

Main Results:

  • Recent extensive studies have found no connection between assisted reproductive techniques and the development of multiple sclerosis.
  • ART is considered effective for women with MS seeking fertility treatments.
  • ART does not pose a significant health risk to women with MS.

Conclusions:

  • Current evidence supports the safety and effectiveness of ART for women with MS.
  • Individualized therapy planning is essential for women with MS undergoing ART.
  • Interdisciplinary collaboration is vital for optimizing IVF timing and minimizing MS exacerbation risks.