Clinical Characteristics and Outcomes of Pediatric Vitamin C Deficiency
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View abstract on PubMed
Summary
This summary is machine-generated.Pediatric vitamin C deficiency is a concern, often linked to poor fruit and vegetable intake. Early detection and dietary intervention are crucial for improving outcomes in children.
Area Of Science
- Pediatrics
- Nutritional Science
- Public Health
Background
- Vitamin C deficiency (scurvy) is under-recognized in children, particularly in Southeast Asia.
- This study investigates clinical features, dietary risks, and outcomes of pediatric vitamin C deficiency.
- Focuses on a tertiary hospital setting in Southern Thailand.
Purpose Of The Study
- To characterize clinical presentations of vitamin C deficiency in children.
- To identify dietary risk factors associated with the condition.
- To evaluate treatment outcomes and inform prevention strategies.
Main Methods
- Retrospective review of medical records for children (1-15 years) diagnosed with vitamin C deficiency (2004-2024).
- Diagnosis based on serum ascorbic acid levels (<0.4 mg/dL) or clinical-radiographic evidence.
- Data included demographics, diet, clinical signs, imaging, lab results, treatment, and outcomes.
Main Results
- 46 children diagnosed; median age 4.8 years, 54.4% with developmental delay.
- Common signs: limb pain (76.1%), refusal to walk (52.2%), bleeding gums (39.1%).
- Low fruit/vegetable intake (73%) and excessive milk consumption linked to deficiency (p<0.05).
Conclusions
- Pediatric vitamin C deficiency remains a significant concern requiring early detection.
- Dietary history is critical for identifying at-risk children and preventing misdiagnosis.
- Parental education on nutrition is essential for reducing incidence and improving outcomes.
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