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Rapidly Progressive Merkel Cell Carcinoma with Atypical Metastatic Pattern-A Case Report and Brief Literature Review
Teodora Gabriela Alexescu1, Denisa Lungu2, Tania Popescu3
14th Medical Discipline, Department of Internal Medicine, "Iuliu Hațieganu" University of Medicine and Pharmacy, Republicii Street, No. 18, 400015 Cluj-Napoca, Romania.
Diagnostics (Basel, Switzerland)
|December 11, 2025
Summary
This case highlights a rare, aggressive Merkel cell carcinoma (MCC) with exceptionally rapid progression and splenic involvement in an 84-year-old male. The findings suggest highly proliferative MCC subtypes may bypass typical metastatic pathways.
Area of Science:
- Oncology
- Dermatology
- Pathology
Background:
- Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skin cancer.
- Incidence is rising in elderly, immunocompromised individuals, and those with UV exposure.
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