Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Perioperative Management of Upper Tract Urothelial Carcinoma: Current Evidence and Future Directions.

Urologia internationalis·2026

Same author

Bilateral testicular uptake in <sup>18</sup>F-DCFPyL PET-CT in prostate cancer patients: report of two cases.

Revista espanola de medicina nuclear e imagen molecular·2026

Same author

Beyond Visualization: Advanced Imaging, Theragnostics and Biomarker Integration in Urothelial Bladder Cancer.

Cancers·2025

Same author

MAML3-fusions modulate vascular and immune tumour microenvironment and confer high metastatic risk in pheochromocytoma and paraganglioma.

Best practice & research. Clinical endocrinology & metabolism·2024

Same author

Bladder Capacity in Women With Overactive Bladder Syndrome: A Cross-sectional Study.

Urology·2023

Same author

A Comprehensive Analysis of Immune Response in Patients with Non-Muscle-Invasive Bladder Cancer.

Cancers·2023

Search research articles

Related Experiment Video

Updated: Jun 27, 2026

Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking

Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking

Published on: November 17, 2023

Redefining Prostate Cancer Precision: Radiogenomics, Theragnostics, and AI-Driven Biomarkers.

Cristina Quicios Dorado¹, Ana Sánchez Ramírez², Marta Pérez Pérez¹

¹Department of Urology, Hospital Universitario de La Princesa, IIS Princesa, Universidad Autónoma de Madrid, 28006 Madrid, Spain.

|December 11, 2025

Summary

This summary is machine-generated.

Advanced imaging, PSMA-targeted therapies, and AI are revolutionizing prostate cancer care. These innovations improve detection, personalize treatment, and advance precision oncology for better patient outcomes.

Keywords:

PET/CT PET/MRI PSMA artificial intelligence circulating tumor cells ctDNA integrative models liquid biopsy personalized medicine prostate cancer radiogenomics radioligand therapy radiomics theragnostics

More Related Videos

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

Detection and Isolation of Cancer in Prostate Biopsies Using Stimulated Raman Histology and Artificial Intelligence

Detection and Isolation of Cancer in Prostate Biopsies Using Stimulated Raman Histology and Artificial Intelligence

Published on: June 10, 2025

Related Experiment Videos

Last Updated: Jun 27, 2026

Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking

Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking

Published on: November 17, 2023

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

Detection and Isolation of Cancer in Prostate Biopsies Using Stimulated Raman Histology and Artificial Intelligence

Detection and Isolation of Cancer in Prostate Biopsies Using Stimulated Raman Histology and Artificial Intelligence

Published on: June 10, 2025

Area of Science:

Oncology
Medical Imaging
Radiochemistry

Background:

Prostate cancer is a leading cause of male cancer mortality globally.
Conventional imaging lacks sensitivity for detecting recurrent or advanced prostate cancer.

Purpose of the Study:

To review recent advancements in prostate cancer diagnostics and therapeutics.
To explore the role of novel imaging, PSMA-targeted agents, radiogenomics, liquid biopsies, and AI in personalized medicine.

Main Methods:

Narrative review of studies from 2015-2025.
Searched PubMed, Embase, and Cochrane databases.
Included advanced imaging, PSMA-theranostics, radiogenomics, liquid biopsy, and AI applications.

Main Results:

PSMA PET/CT surpasses conventional imaging in detecting and restaging prostate cancer.
Lutetium-177-PSMA-617 is standard for metastatic castration-resistant prostate cancer; alpha-emitters are under investigation.
Radiogenomics, liquid biopsies (ctDNA, CTCs, AR-V7), and AI enhance molecular insights and imaging interpretation, supporting personalized risk stratification.

Conclusions:

Imaging and theranostic advancements are transforming prostate cancer management.
These innovations bridge molecular biology and clinical practice for precision oncology.
Integrative models combining imaging, genomic, and liquid biopsy data enable personalized therapeutic decisions.