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In Vitro Evaluation of Multifocal Intraocular Lenses Based on the Point Spread Function: Optical Performance and Halo

Anabel Martínez-Espert1, Salvador García-Delpech2, Walter D Furlan1

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This study compared multifocal intraocular lenses (MIOLs), finding that extended depth-of-focus (EDoF) designs produced fewer halos than trifocal options. Optical performance varied by lens, pupil size, and light conditions.

Keywords:
chromatic aberrationhalosmultifocal intraocular lensoptical bench

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Area of Science:

  • Ophthalmology
  • Optical Engineering
  • Biomedical Optics

Background:

  • Trifocal and extended depth-of-focus (EDoF) multifocal intraocular lenses (MIOLs) are crucial for visual restoration after cataract surgery.
  • In vitro evaluation of MIOLs is essential for surgeons to select optimal lenses for patients.
  • Understanding lens optical behavior aids in improving surgical outcomes and spectacle independence.

Purpose of the Study:

  • To quantitatively assess and compare the optical performance of leading trifocal and EDoF MIOLs.
  • To evaluate halo formation and chromatic aberration characteristics of selected intraocular lenses.
  • To provide evidence-based data for informed MIOL selection in clinical practice.

Main Methods:

  • Four MIOLs (FineVision POD F, Acriva Trinova Pro C, AT LARA 829MP, AcrySof IQ Vivity) were tested on an optical bench.
  • Through-focus modulation transfer function (TF-MTF) and area under the MTF (MTFa) were calculated from point spread functions (PSF).
  • Halo formation was qualitatively analyzed, and performance was assessed under varying pupil sizes and wavelengths.

Main Results:

  • FineVision POD F and Acriva Trinova Pro C demonstrated trifocal behavior, with performance dependent on pupil size and wavelength.
  • AT LARA 829MP showed bifocal characteristics in monochromatic light but EDoF in polychromatic light.
  • AcrySof IQ Vivity exhibited an EDoF profile and the least halo formation among tested lenses.

Conclusions:

  • Significant differences exist in the optical and chromatic performance of trifocal versus EDoF intraocular lenses.
  • EDoF lenses generally produced fewer halos compared to trifocal designs.
  • These findings support personalized MIOL selection to enhance visual outcomes and spectacle independence.