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Immersive, Open-World Virtual Reality for Dementia Care: NeuroVRX Pilot Study
Martin Eckert1,2, Thomas Ostermann2, Jan Peter Ehlers2
1Stabsstelle für Digitalisierung und Wissensmanagement, Hochschule Hamm-Lippstadt, 59063 Hamm, Germany.
Journal of Clinical Medicine
|December 11, 2025
Summary
This pilot study found that immersive, open-world virtual reality (VR) is a feasible, safe, and acceptable intervention for individuals with dementia. VR offers cognitive and motor stimulation, supporting its use in future therapeutic trials.
Area of Science:
- Gerontology
- Neuroscience
- Human-Computer Interaction
Background:
- Alzheimer's disease and related dementias present growing global health and economic challenges.
- Cognitive Stimulation Therapy (CST) offers non-pharmaceutical benefits for dementia patients.
- Digital and virtual reality (VR) interventions for dementia, particularly in open-world environments, remain underexplored.
Purpose of the Study:
- To assess the feasibility, acceptability, and safety of an immersive, open-world VR application for people diagnosed with dementia.
- To explore the potential of VR as a tool for cognitive and motor stimulation in this population.
Main Methods:
- A single-arm, unrandomised pilot study involving three male participants with dementia.
- Participants engaged in a single VR session within an immersive, open-world environment, navigating freely via seated arm and head movements.
- Data collected included session duration, virtual movement metrics, and participant feedback via questionnaires and anecdotal reports.
Main Results:
- All participants completed the VR session without adverse events or cybersickness.
- Average session time was 28 minutes, with participants virtually covering 0.9 km (1210 steps).
- Questionnaires indicated positive usability and acceptance; anecdotal feedback highlighted immersion and autobiographical stimulation with minimal mood changes.
Conclusions:
- Immersive, open-world VR is a feasible, safe, and well-accepted intervention for individuals with dementia.
- The combination of advanced hardware and exploratory VR software provides cognitive and motor stimulation.
- Results support the potential of 3D exploratory VR applications and warrant further controlled trials for therapeutic efficacy assessment.
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