Association Between Congenital Gastrointestinal Malformation Outcome and Largely Asymptomatic SARS-CoV-2 Infection in Pediatric Patients-A Systematic Review
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View abstract on PubMed
Summary
This summary is machine-generated.Pediatric patients with congenital gastrointestinal malformations and perioperative SARS-CoV-2 infection generally experience mild illness and good surgical outcomes. COVID-19 positivity should not delay necessary surgeries if infection control is maintained.
Area Of Science
- Pediatric Surgery
- Infectious Diseases
- Gastroenterology
Background
- Limited evidence exists on surgical outcomes for children with congenital gastrointestinal malformations and perioperative SARS-CoV-2 infection.
- Understanding these outcomes is crucial for managing pediatric surgical cases during the pandemic.
Purpose Of The Study
- To systematically review and analyze the scientific evidence on surgical outcomes in children with congenital gastrointestinal malformations who also have SARS-CoV-2 infection.
- To assess the impact of perioperative SARS-CoV-2 infection on surgical outcomes in this pediatric population.
Main Methods
- Systematic review of observational studies from PubMed and Embase (up to August 2024).
- Inclusion of studies reporting data on children with congenital gastrointestinal malformations and SARS-CoV-2 status.
- Quality assessment using Joanna Institute (JBI) checklist and adherence to PRISMA guidelines.
Main Results
- Eight studies involving 29 pediatric patients were included; most were neonates (75%) with upper (62%) or lower (38%) gastrointestinal anomalies.
- SARS-CoV-2 infection was mostly detected via routine screening (>95%).
- 85% of patients were discharged home; no direct COVID-19-associated surgical mortality or major complications were observed, though routine morbidity occurred.
Conclusions
- Pediatric patients with congenital gastrointestinal malformations and perioperative SARS-CoV-2 infection typically present with mild illness and achieve favorable surgical outcomes.
- SARS-CoV-2 positivity should not impede essential surgical interventions when infection control measures are in place.
- Further standardized, multicenter studies are necessary to refine perioperative risk assessment and management strategies for this cohort.
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