Efficacy of Injectable Calcium Composite Bone Substitute Augmentation for Osteoporotic Intertrochanteric Fractures: A...

Area of Science:

• Orthopedic Surgery
• Biomaterials Science
• Geriatric Medicine

Background:

• Osteoporotic intertrochanteric fractures (ITFs) in older adults pose significant risks of fixation failure, pain, and mortality.
• Current fixation methods may lack sufficient stability, necessitating improved augmentation strategies.
• Injectable calcium composite bone substitute (ICCBS) is a potential solution for enhancing construct stability and bone healing.

Purpose of the Study:

• To evaluate the efficacy of ICCBS augmentation in managing osteoporotic ITFs.
• To assess the impact of ICCBS on fracture healing, construct stability, and functional recovery.
• To compare outcomes between patients receiving ICCBS augmentation and those undergoing standard fixation.

Main Methods:

• A multicenter, prospective, non-randomized controlled study.
• Patients with osteoporotic ITFs received either standard proximal femoral nail fixation or fixation augmented with ICCBS.
• Outcomes including time to union, pain scores, ambulatory status, and fixation failure were prospectively collected.

Main Results:

• No significant difference in the time to radiographic bone union between groups.
• ICCBS augmentation group showed significantly lower postoperative pain scores up to 6 weeks.
• Reduced lag screw sliding and varus collapse were observed in the ICCBS group at bone union.

Conclusions:

• ICCBS augmentation may enhance early postoperative pain control and construct stability in osteoporotic ITFs.
• The effect of ICCBS on fracture healing and long-term functional outcomes remains to be determined.
• High-quality randomized trials are needed to validate these preliminary findings.