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Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
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Electronic enhancement to decrease rejection of blood type verification specimens.

V Rakesh Sethapati1, Emily Morton2, Sashika Kilambi2

  • 1Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

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|December 11, 2025
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Summary
This summary is machine-generated.

An electronic enhancement significantly reduced blood type verification (BTV) rejections by preventing label printing until after the initial type and screen (TNS) sample collection. This improves patient safety and timely blood product availability.

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Area of Science:

  • Transfusion Medicine
  • Clinical Pathology
  • Health Informatics

Background:

  • Association for the Advancement of Blood & Biotherapies (AABB) standards mandate current type & screen (TNS) and blood type verification (BTV) for crossmatched transfusions.
  • BTV requires a second, independently collected blood specimen with reconfirmed patient identity.
  • Policy mandates TNS and BTV samples collected at different times; same-time collection leads to BTV rejection.

Purpose of the Study:

  • To describe an electronic enhancement designed to decrease blood type verification (BTV) rejection rates.
  • To improve the efficiency and accuracy of pre-transfusion blood sample processing.

Main Methods:

  • Implemented an electronic health record (EHR) enhancement that prevents BTV label printing until the TNS sample is documented as collected.
  • Ensured BTV specimen collection is only accessible after initial TNS sample verification, enforcing independent collection.

Main Results:

  • Overall BTV rejections decreased from an average of 66 per month to 37 per month post-implementation.
  • BTV rejections as a percentage of total specimen rejections dropped from 45% to 2% monthly.

Conclusions:

  • A simple electronic enhancement drastically reduced BTV rejections.
  • Improved patient safety through timely provision of crossmatched blood products.
  • Reduced the incidence of sample redraws, optimizing laboratory workflow.