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Related Concept Videos

Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

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A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
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Hemorrhagic Stroke ll: Pathophysiology01:29

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A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
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Kratom-Associated Diffuse Alveolar Haemorrhage: A Clinical Image.

Venkatkiran Kanchustambham1,2, Kara Johnson1,2

  • 1Sanford Health, Pulmonary & Critical Care Medicine Fargo North Dakota USA.

Respirology Case Reports
|December 11, 2025
PubMed
Summary
This summary is machine-generated.

Heavy kratom ingestion led to diffuse alveolar hemorrhage in a patient. Medical imaging and bronchoscopy confirmed the condition, ruling out vaping as a cause.

Keywords:
BALKratombronchoscopydiffuse alveolar haemorrhagelung injury

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Area of Science:

  • Toxicology
  • Pulmonary Medicine
  • Internal Medicine

Background:

  • Kratom (Mitragyna speciosa) is a tropical tree native to Southeast Asia.
  • Its leaves are used for medicinal purposes, including pain relief and recreational use.
  • Adverse effects of kratom, such as liver injury and psychosis, have been reported.

Purpose of the Study:

  • To report a case of diffuse alveolar hemorrhage following heavy kratom ingestion.
  • To investigate the potential link between kratom use and pulmonary complications.
  • To differentiate kratom-induced injury from other potential causes of alveolar hemorrhage.

Main Methods:

  • A case report of a patient presenting with respiratory symptoms after kratom use.
  • Diagnostic procedures included chest imaging (X-ray, CT scan) and bronchoscopy with bronchoalveolar lavage.
  • Vaping history was specifically assessed and excluded as a confounding factor.

Main Results:

  • The patient developed acute diffuse alveolar hemorrhage.
  • Chest imaging revealed bilateral infiltrates consistent with hemorrhage.
  • Bronchoscopy confirmed active bleeding from the alveoli.
  • Heavy kratom ingestion was identified as the likely trigger, with vaping excluded.

Conclusions:

  • Heavy kratom ingestion can be a potential cause of diffuse alveolar hemorrhage.
  • Pulmonary toxicity should be considered in patients with unexplained alveolar hemorrhage and a history of kratom use.
  • Further research is needed to elucidate the mechanisms of kratom-induced pulmonary injury.