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Obesity

Obesity

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Drug Dosing: Obese Patients

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Related Experiment Video

Updated: Jan 8, 2026

Multidisciplinary Approach to Obesity Management: A Case Report

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Commercial products and programmes in obesity management.

Z Bayat¹, S A Bhana², M Conradie-Smit³

¹ivision of Endocrinology, Department of Internal Medicine, Helen Joseph Tertiary Hospital and University of the Witwatersrand, Johannesburg, South Africa.

South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde

|December 11, 2025

Summary

Commercial weight loss programs may aid mild weight loss and improve type 2 diabetes markers in adults. However, over-the-counter products lack evidence, and programs do not reliably improve blood pressure or lipid control in obesity.

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Area of Science:

Obesity management and metabolic health.
Evidence-based recommendations for weight control interventions.

Background:

Overweight and obesity are significant global health concerns.
Effective and evidence-based weight management strategies are crucial for public health.

Purpose of the Study:

To evaluate the efficacy of commercial weight loss programs and products.
To provide recommendations for the management of overweight and obesity.

Main Methods:

Systematic review of evidence for commercial weight loss interventions.
Assessment of impact on weight, glycated haemoglobin, blood pressure, and lipid profiles.

Main Results:

Commercial programs show potential for mild-to-moderate weight loss and short-term HbA1c reduction in type 2 diabetes.
Over-the-counter products lack supporting evidence for obesity management.
Commercial programs do not demonstrate effectiveness in improving blood pressure or lipid control in obesity.

Conclusions:

Certain commercial programs may offer modest benefits for weight loss and glycemic control in specific populations.
Lack of evidence precludes recommendation of over-the-counter weight loss products.
Commercial programs are not recommended for improving cardiovascular risk factors in obesity.