Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hand hygiene01:23

Hand hygiene

5.4K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
5.4K
Tonsillitis II: Management01:26

Tonsillitis II: Management

384
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
384
Pneumonia IV: Management01:28

Pneumonia IV: Management

726
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
726
Urinary Tract Infection IV: Nursing Management01:17

Urinary Tract Infection IV: Nursing Management

400
In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs...
400
  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Paediatrics
  9. Infant And Child Health
  11. Repurposing Povidone-iodine For The Treatment Of Chronic Suppurative Otitis Media In Nigerian Children

Repurposing Povidone-Iodine for the Treatment of Chronic Suppurative Otitis Media in Nigerian Children

Mercy E Jatto1, Adebolajo A Adeyemo1, Ayotunde J Fasunla1

  • 1University College Hospital.

Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [And] European Academy of Otology and Neurotology
|December 11, 2025

Related Experiment Videos

A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset Callithrix jacchus
06:55

A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset Callithrix jacchus

Published on: February 27, 2018

9.1K
Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection
05:32

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

Published on: September 21, 2015

33.5K
Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
03:40

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Published on: April 25, 2025

1.1K

View abstract on PubMed

Summary
This summary is machine-generated.

Povidone-iodine ear irrigation is as effective as ciprofloxacin drops for treating chronic suppurative otitis media (CSOM) in children. Oral antibiotics showed negligible benefit, suggesting simpler treatments may suffice for uncomplicated CSOM.

Area of Science:

  • Otolaryngology
  • Pediatric Infectious Diseases
  • Clinical Trials

Background:

  • Chronic suppurative otitis media (CSOM) is a common cause of hearing loss in children.
  • Antibiotic eardrops are the standard treatment, but rising resistance and treatment failures necessitate alternative therapies.
  • Exploring novel treatments is crucial due to increasing antibiotic resistance in CSOM management.

Purpose of the Study:

  • To compare the efficacy of povidone-iodine ear irrigation versus ciprofloxacin ear drops for treating uncomplicated CSOM in children.
  • To evaluate the added benefit of oral antibiotics in conjunction with topical treatments for CSOM.
  • To assess the effectiveness of povidone-iodine irrigation as a standalone treatment for CSOM.

Main Methods:

  • An 18-month randomized clinical trial involving 361 children aged 6 months to 14 years with uncomplicated CSOM.
Keywords:
Chronic suppurative otitis mediaMiddle ear cleftPovidone-iodine

Related Experiment Videos

A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset Callithrix jacchus
06:55

A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset Callithrix jacchus

Published on: February 27, 2018

9.1K
Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection
05:32

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

Published on: September 21, 2015

33.5K
Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
03:40

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Published on: April 25, 2025

1.1K
  • Three intervention groups: (a) povidone-iodine irrigation + oral amoxicillin-clavulanic acid, (b) ciprofloxacin drops + oral amoxicillin-clavulanic acid, (c) povidone-iodine irrigation alone.
  • Treatment duration was 4 weeks, with assessments at 4 weeks and 3 months post-intervention.

    • Main Results:

    • Otorrhea resolution rates were high and comparable across all groups (92.7%-93.7%).
    • Tympanic membrane healing rates were 11.7% (group a), 12.7% (group b), and 15.6% (group c).
    • Pathologic isolates were absent post-treatment in 75% (group a), 80.3% (group b), and 74.5% (group c) of cases.

    Conclusions:

    • 0.5% povidone-iodine aural irrigation is non-inferior to 0.3% ciprofloxacin otic suspension for uncomplicated CSOM.
    • The addition of oral antibiotics (amoxicillin-clavulanic acid) provided negligible additional benefit in treating uncomplicated CSOM.
    • Povidone-iodine ear irrigation represents an effective alternative treatment for uncomplicated CSOM, potentially reducing reliance on oral antibiotics.