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Updated: Jan 8, 2026

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
Published on: May 26, 2023
Comparative Analysis of Postoperative Recovery and Analgesia in Gynecologic Laparoscopic Surgery with Total
Wei Wang1, Yong Tang2, Yanqi Meng2
1Department of Anesthesiology, the First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Institute of Anesthesia and Respiratory Critical Medicine Shandong Provincial Clinical Research Center of Anesthsiology, Jinan, Shandong Province, The People's Republic of China.
Objective:
This study aims to unravel the clinical effects of total intravenous anesthesia (TIVA) versus combined intravenous-inhalational anesthesia, each with ultrasound-guided transversus abdominis plane (TAP) block, in gynecologic laparoscopic surgery.
Methods:
In this prospective randomized controlled trial, 100 patients undergoing gynecologic laparoscopic surgery were randomly assigned to either a control group (balanced inhalation anesthesia + TAP block) or an observation group (TIVA + TAP block) (n = 50 each). Postoperative recovery, pain scores (VAS at 2, 6, 12, 24, and 48 h), hemodynamics (SpO2, heart rate, SBP) at key surgical stages, and stress markers (cortisol, PGE2), and complications were recorded.
Results:
Baseline characteristics were comparable. The observation group showed faster spontaneous respiration recovery, awakening, and extubation (all p < 0.05), though ambulation, flatus, and hospital stay did not differ (p > 0.05). VAS scores were lower in the observation group at all time points (p < 0.05). Hemodynamics remained stable in both groups. Postoperative cortisol and PGE2 rose in both groups but were lower in the observation group (p < 0.05). Nausea/vomiting incidence was reduced with TIVA (p < 0.05).
Conclusion:
TIVA combined with ropivacaine TAP block accelerates early recovery, improves analgesia, attenuates surgical stress, and reduces nausea/vomiting.
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