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An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
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Giant Cell Arteritis Causing Isolated Pulmonary Artery Aneurysm

Ivka R Stimach1, Adil F Vural2, Marissa Edmiston3

  • 1Department of Internal Medicine, MetroHealth Medical Center/Case Western Reserve University, Cleveland, Ohio, USA.

JACC. Case Reports
|December 11, 2025
PubMed
Abstract

Insights

Pulmonary artery aneurysms (PAA) are rare. This case details a PAA caused by giant cell arteritis, a rare autoimmune vasculitis, successfully treated with surgery, highlighting an unusual etiology and treatment approach.

Area of Science:

  • Cardiovascular Medicine
  • Rheumatology
  • Vascular Surgery

Background:

  • Pulmonary artery aneurysms (PAA) are rare, with an incidence of approximately 1 in 14,000.
  • Etiologies for PAA are diverse, including malignancy, infection, congenital conditions, autoimmune diseases, and vasculitis.
  • Giant cell arteritis (GCA) is an uncommon cause of PAA, typically affecting large and medium-sized vessels.
Keywords:
giant cell arteritispulmonary artery aneurysm

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