Related Experiment Video
Updated: May 12, 2026

Isolation and Ex Vivo Culture of Vδ1+CD4+γδ T Cells, an Extrathymic αβT-cell Progenitor
Published on: December 7, 2015
Impact of Evolving Life Circumstances on Emerging Adults with Type 1 Diabetes: Discoveries from the Tübingen
Silas Friz1, Roland Schweizer2, Clara Hayn1
1Pediatric Diabetology, University Children's Hospital, Tübingen, Germany.
Introduction:
Transition from pediatric to adult care present challenges for patients with chronic diseases. The objective of the study was to identify factors associated with metabolic control in childhood-onset type 1 diabetes (T1D) following transfer to adult care. Additionally, we aimed to characterize sociodemographic parameters and to compare these data with those of the general population.
Methods:
Contact of 281 patients transferred from pediatric to adult care between 1998 and 2021 yearly by questionnaire to provide information regarding their current hemoglobin A1c (HbA1c), type of care, type of therapy, occupational situation, living situation, marital status, and parental status. Data were analyzed using a mixed cross-sectional longitudinal approach.
Results:
A total of 205 patients responded at least once (mean age: 27.7 years). Women were more frequently treated with pump therapy than men (p < 0.05). HbA1c levels reported by men did not significantly differ from those reported by women before and after transfer. Individuals employed in academic jobs after transfer had significantly lower HbA1c levels before and after transfer than those in nonacademic jobs, while the differences between individuals who were in vocational training and those pursuing studies were most pronounced (7.4 ± 1.0%, 57 ± 13 mmol/mol vs. 7.0 ± 0.8%, 53 ± 15 mmol/mol, p < 0.05). Moreover, among individuals aged 30-40, those with T1D exhibited a lower prevalence of having children (38.0% vs. 52.7%) and being married (40.5% vs. 55.3%) compared to general population.
Conclusions:
Psychosocial life circumstances that are considered more stable in early adulthood, such as being a parent and working in academic occupation, were positively associated with metabolic control.
More Related Videos
05:52Long-Term, Serum-Free Cultivation of Organotypic Mouse Retina Explants with Intact Retinal Pigment Epithelium
Published on: November 25, 2020
08:56Modeling Mitochondrial Disease Using Brain Organoids: A Focus on Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes
Published on: October 10, 2025
Related Concept Videos
Emerging Adulthood
Type I Diabetes I: Introduction
Type I Diabetes II: Pathophysiology
Type I Diabetes III: Clinical Manifestations
Type II Diabetes I: Introduction
Type II Diabetes II: Pathophysiology