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Structured pharmaceutical interviews enhance knowledge and medication adherence in DOAC therapy: Insights from the
Samuel D Cohen1, François Bouvier2, Claire-Marie Tissot3
1Hospital Pharmacy, Bégin Military Teaching Hospital, Saint-Mandé 94160, France; Hospital Pharmacy, Montreuil Hospital, Montreuil 93100, France; Sorbonne University, CIC 1901, Department of Pharmacology, La Pitié Salpêtrière Hospital, Paris 75651, France.
Structured pharmaceutical interviews (SPIs) significantly improve patient knowledge and adherence to direct oral anticoagulants (DOACs). This intervention also led to a reduction in clinical complications, optimizing anticoagulant therapy.
Area of Science:
- Pharmacology
- Patient Education
- Clinical Pharmacy
Background:
- Direct oral anticoagulants (DOACs) are essential treatments for atrial fibrillation and venous thromboembolism.
- Enhancing patient understanding of DOAC therapy is crucial for improving adherence and minimizing complications.
Purpose of the Study:
- To assess the impact of structured pharmaceutical interviews (SPIs) on patient knowledge and medication adherence for DOACs.
- To evaluate the effect of SPIs on clinical complications related to DOAC therapy.
Main Methods:
- A study involving patients newly prescribed DOACs across two centers, with one center providing SPIs.
- Standardized questionnaires assessed knowledge and adherence at 3 and 6 months.
- Multivariate logistic regression analyzed predictors of improved outcomes, adjusted for propensity score.
Main Results:
- Patients receiving SPIs showed significantly higher satisfactory knowledge (74% vs. 12%) and good medication adherence (86% vs. 64%) at 3 months.
- SPIs were strong predictors of improved knowledge and adherence.
- The intervention group experienced fewer clinical complications at 6 months (0 vs. 9).
Conclusions:
- Structured pharmaceutical interviews significantly improve patient knowledge and adherence to DOAC therapy.
- SPIs contribute to a reduction in clinical complications associated with DOACs.
- Integrating SPIs into routine practice could optimize anticoagulant management.
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