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Updated: Jan 8, 2026

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery
Published on: November 5, 2019
Hide and seek: Cryptococcus evasion of microglial sensing enables meningitis
Jessica C Hargarten1, Amariliz Rivera2
1Department of Pathology, Immunology, and Laboratory Medicine and Center for Immunity and Inflammation, New Jersey Medical School, Rutgers University, Newark, NJ, USA.
None:
In this issue of Cell Host & Microbe, Reyes et al.1 uncovered that delayed microglial activation provides Cryptococcus a temporal advantage in establishing central nervous system infections in a CD4+ T cell-competent setting. This delay carries implications for the development of severe cryptococcal meningoencephalitis and post-infection syndrome in humans.
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