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Related Concept Videos

Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Bone Remodeling and Repair01:31

Bone Remodeling and Repair

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...

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[Functional Extremity Reconstruction: Just a Modern Term or Reconstruction 2.0?]

Albrecht Heine-Geldern1, Raffaela Faulhaber1, Alexander Hach1

  • 1Klinik für Plastische Chirurgie, Hand- und Rekonstruktive Mikrochirurgie, Handtrauma- und Replantationszentrum, BG Unfallklinik Frankfurt am Main gGmbH, Frankfurt, Germany.

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PubMed
Summary
This summary is machine-generated.

Orthoplastic surgery integrates orthopedic and plastic surgery for complex limb reconstruction, emphasizing functional restoration beyond simple defect closure. This review explores techniques for a comprehensive "reconstruction 2.0" approach, aiming for improved patient outcomes.

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Area of Science:

  • Orthoplastic Surgery
  • Microsurgery
  • Reconstructive Surgery

Background:

  • Orthoplastic surgery is a vital interdisciplinary field for complex limb reconstructions.
  • Modern approaches extend beyond skin closure to reconstruct all tissue types and functions.
  • The concept of

Purpose of the Study:

  • To review and synthesize modern microsurgical and plastic surgery techniques for orthoplastic limb reconstruction.
  • To propose an applicable overall concept for contemporary orthoplastic limb reconstruction.
  • To address the lack of a universal definition for

Main Methods:

  • Literature review of microsurgical and plastic surgery techniques.
  • Analysis of clinical experience in orthoplastic limb reconstruction.
  • Evaluation of interdisciplinary treatment planning and functional endpoints.

Main Results:

  • Numerous techniques have evolved over six decades, focusing on functional limb reconstruction.
  • A comprehensive approach requires addressing skin, bone, muscle, nerves, vasculature, and lymphatics.
  • Interdisciplinary board meetings are crucial for establishing treatment plans focused on functional goals.

Conclusions:

  • Orthoplastic surgery represents a paradigm shift towards "reconstruction 2.0" for limb defects.
  • A unified concept is needed to integrate diverse techniques and achieve functional endpoints like mobility and reintegration.
  • Further development is required to establish a clear international definition of "functionality" in this context.