Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

543
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
543

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Safety and efficacy of a feed additive consisting of sodium alginate for all animal species (ALGAIA).

EFSA journal. European Food Safety Authority·2022
Same author

Safety and efficacy of a feed additive consisting of an essential oil from the leaves of <i>Agathosma betulina</i> (P.J. Bergius) Pillans (buchu leaf oil) for use in all animal species (FEFANA asbl).

EFSA journal. European Food Safety Authority·2022
Same author

Safety and efficacy of a feed additive consisting of an extract of olibanum from <i>Boswellia serrata</i> Roxb. ex Colebr. for use in dogs and horses (FEFANA asbl).

EFSA journal. European Food Safety Authority·2022
Same author

Assessment of the feed additive consisting of <i>Lactiplantibacillus plantarum</i> (formerly <i>Lactobacillus plantarum</i>) NCIMB 30236 for all animal species for the renewal of its authorisation (BioCC OÜ).

EFSA journal. European Food Safety Authority·2022
Same author

Safety and efficacy of the feed additive consisting of <i>Lactobacillus acidophilus</i> CECT 4529 (<i>Lactobacillus acidophilus</i> D2/CSL) for all poultry species and categories and all ornamental birds (Centro Sperimentale del Latte S.r.l).

EFSA journal. European Food Safety Authority·2022
Same author

Efficacy of a feed additive consisting of endo-1,4-beta-xylanase produced by <i>Trichoderma citrinoviride</i> (IMI SD 135) (HOSTAZYM<sup>®</sup> X) for sows in order to have benefits in piglets (Huvepharma NV).

EFSA journal. European Food Safety Authority·2022

Related Experiment Video

Updated: Jan 8, 2026

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
06:34

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS

Published on: July 11, 2016

19.8K

Why Is the Current Monitoring of Rodentibacter spp. Exclusively by Molecular Methods Insufficient?

Laurentiu Benga1, W Peter M Benten1, Sabine J Bischoff1

  • 11Institute for Laboratory Animal Science, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany; and.

Journal of the American Association for Laboratory Animal Science : JAALAS
|December 11, 2025
PubMed
Summary

Current molecular methods for monitoring Rodentibacter species in lab rodents risk missing opportunistic pathogens due to a lack of host specificity and limited test availability. This can lead to importing contaminated animals.

More Related Videos

A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice
07:54

A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice

Published on: July 25, 2017

14.7K
The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis
11:04

The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis

Published on: February 19, 2013

27.0K

Related Experiment Videos

Last Updated: Jan 8, 2026

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
06:34

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS

Published on: July 11, 2016

19.8K
A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice
07:54

A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice

Published on: July 25, 2017

14.7K
The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis
11:04

The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis

Published on: February 19, 2013

27.0K

Area of Science:

  • Microbiology
  • Laboratory Animal Science

Background:

  • The Rodentibacter genus, formerly Pasteurella pneumotropica, comprises 12 species of opportunistic pathogens common in laboratory rodents.
  • These bacteria are part of the oral and genital microbiome and can cause pathophysiological issues in colonized animals.

Purpose of the Study:

  • To highlight the implications of Rodentibacter species diversity and host specificity in laboratory rodent health monitoring.
  • To emphasize the limitations of current monitoring strategies and the risks associated with relying solely on molecular diagnostics.

Main Methods:

  • Review of current literature on Rodentibacter species, their host specificity, and diagnostic methods.
  • Analysis of the prevalence and significance of Rodentibacter spp. in laboratory mice and rats.

Main Results:

  • Rodentibacter species exhibit host specificity, with distinct species found in mice (e.g., R. pneumotropicus, R. heylii) and rats (e.g., R. ratti, R. heidelbergensis).
  • R. haemolyticus prevalence in both species requires further investigation.
  • Cross-contamination between mice and rats occurs, complicating monitoring.
  • Current molecular diagnostics often focus on a limited number of species, neglecting others.

Conclusions:

  • Existing health monitoring strategies may fail to detect all relevant Rodentibacter taxa due to a lack of host-specific and comprehensive molecular tests.
  • Reliance on incomplete molecular assays poses a risk for importing Rodentibacter-positive laboratory rodents.