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Identifying priority countries for scaling up small-quantity lipid-based nutrient supplements.

Navideh Noori1, Christine P Stewart2, Christine M McDonald2,3

  • 1Institute for Disease Modeling, Gates Foundation, Seattle, Washington, USA Navideh.Noori@gatesfoundation.org.

BMJ Global Health
|December 11, 2025
PubMed
Summary
This summary is machine-generated.

Small-quantity lipid-based nutrient supplements (SQ-LNS) can prevent child malnutrition and mortality. Scaling up SQ-LNS in high-burden countries, primarily in Sub-Saharan Africa, is crucial to address the global nutrition crisis.

Keywords:
Child healthNutritionPrevention strategiesStunting

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Area of Science:

  • Global Health
  • Nutritional Science
  • Pediatric Health

Background:

  • Undernutrition causes nearly half of deaths in children under 5 globally.
  • Small-quantity lipid-based nutrient supplements (SQ-LNS) are proven to prevent wasting, stunting, anemia, and mortality in children aged 6-23 months in low- and middle-income countries (LMICs).
  • The current global food insecurity and nutrition crisis necessitates urgent scale-up of effective preventive interventions like SQ-LNS.

Purpose of the Study:

  • To identify countries with the highest burden of child wasting, stunting, and mortality to prioritize SQ-LNS scale-up.
  • To assess the potential impact of SQ-LNS on child mortality, stunting, and wasting using a care cascade model.
  • To identify high-burden subnational regions within the top 20 countries for targeted interventions.

Main Methods:

  • Analysis of national survey data (Demographic and Health Survey, Multiple Indicator Cluster Surveys) and the Lives Saved Tool to identify countries with the highest child malnutrition and mortality burdens.
  • Application of a care cascade model using national-level estimates to project the impact of SQ-LNS.
  • Subnational analysis in the 20 highest-burden countries using the most recent available survey data.

Main Results:

  • The top 20 countries with the highest burden of child wasting, stunting, and mortality were identified, with many located in Sub-Saharan Africa and some in South/Southeast Asia.
  • Some identified countries had survey data older than 10 years, highlighting potential data gaps.
  • The care cascade model indicated that widespread provision of SQ-LNS could avert a substantial number of stunting and wasting cases and deaths.
  • Several high-burden countries also face significant acute food insecurity.

Conclusions:

  • The majority of the top 20 countries are concentrated in Sub-Saharan Africa, with others in South and Southeast Asia.
  • This geographical clustering emphasizes the critical need for focused interventions in these regions to combat child malnutrition.
  • Targeted scale-up of SQ-LNS in these high-burden areas presents a significant opportunity to reduce child mortality and morbidity.