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Advancing observer-reported outcome measurement: development of the MOOD-AS for observing distress in Angelman

Sean N Halpin1, Doesjka A Hagenaar2,3, Sarah Nelson Potter4

  • 1GenOmics and Translational Research Center, RTI International, 3040 East Cornwallis Road, Research Triangle Park, Durham, NC, 27709, 2194, USA. snhalpin@rti.org.

Journal of Patient-Reported Outcomes
|December 11, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Outcome measure developmentQualitative methodsRare disease research

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Socioemotional Development during Infancy01:30

Socioemotional Development during Infancy

Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
Primary Temperament Types
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